Research and Insights

Developing and contributing to important medical research

As an organisation we are proud to participate in medical research projects. Research projects are vital in supporting the advancement of medical science.

This means we can help to find better ways to diagnose and treat medical conditions, and improve the kind of care we offer our patients.

We are developing this area of work and within some of our practices we have been able to invite patients to take part in research. Many of these studies involve developing diagnostic tests and treatments which would not be available otherwise.

Dr Zishan Ali is our National Research lead, he is also leading on research for our division in Wokingham, South East England. Dr Zishan Ali pictured below with our research nurse Belinda I’Anson:

zishan research image



Our current list of research studies is detailed below. If you are interested in taking part, please speak to your GP practice to find out if your practice is participating.

Current research studies:

CLASP 5 - Cancer: Life affirming survivorship support in primary care

CCP - Co-ordinated Programme to Prevent Arthritis: Can We Identify Arthritis at a Pre-Clinical Stage

Barack d - Benefits of Aldosterone Receptor Antagonism in Chronic Kidney Disease

Decide - effectiveness of a dapagliflozin compared to Standard of Care

COPD – a post-authorization Safety (PAS) Observational Cohort Study to Quantify the Incidence and Comparative Safety of Selected Cardiovascular and Cerebrovascular Events in COPD Patients Using Inhaled UMEC/VI Combination or Inhaled UMEC versus Tiotropium


Completed studies

We would like to thank all our patients who have taken part in the studies mentioned below. Without your help we would not be able to advance our knowledge on these medical problems.

Af gen UK - Long-term Registry of Patients with Atrial Fibrillation UK Extension (AF-GEN-UK) Study

CONDUCT - COllectioN Devices to reduce Urine ConTamination

HOME BP - Home & Online Management and Evaluation of Blood Pressure

ARRISA - At-Risk Registers Integrated into primary care to Stop Asthma crises in the UK

PACT - Personalised medicine for Asthma ConTro

PLUS - pic site - A Phase 4, Double-Blind, Randomized, Placebo-controlled, Multi-Center Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Men with Overactive Bladder (OAB) Symptoms While Taking the Alpha Blocker Tamsulosin Hydrochloride for Lower Urinary Tract Symptoms (LUTS) due to Benign Prostatic Hyperplasia (BPH).

INVICTUS - A phase IIb study to determine the safety and efficacy of candidate INfluenza Vaccine MVA-NP+M1 in combination with licensed InaCTivated influenza vaccine in adults aged 65 years and above

OPTIMISE- Optimising treatment for mild systolic hypertension in the elderly: a randomised controlled trial.

PROLIA - Osteoporosis diagnosis and treatment in community-dwelling women ≥70 Years of age managed in Primary Care settings in Europe. A Cross-Sectional Observational Study

ALICE: Antivirals for influenza Like Illness? Clinical and Cost effectiveness in primary care 

CREDENCE - (Canagliflozin and Renal Events in Diabetes with Established Nephropathy Clinical Evaluation). The objective of the study is to examine whether canagliflozin can slow the progression of diabetic nephropathy, a form of renal impairment that is the most common cause of end-stage renal disease worldwide.

CANDID - This trial looked for patients to help doctors to develop guidelines in the future for patients who currently have bowel or lung symptoms who may then later on develop either bowel or lung cancer respectively.

ARCHIE (The early use of Antibiotics for at Risk Children with InfluEnza in primary care) 

TASMINH4 (Telemonitoring and/or self-monitoring of blood pressure in hypertension) –  Our research aims to find out whether high blood pressure is better controlled using blood pressure readings taken by patients at home compared to clinic readings.

TOAST (Treatment Options without Antibiotics for Sore Throat) – Do oral corticosteroids provide clinical and cost effective symptom relief for sore throat?

OSAC (Oral Steroids for Acute Cough) – a study aiming to find out whether giving people a 5 day course of steroid tablets can help treat their chest infection.

DARE (Diabetes Alliance for Research in England) – This study is aiming to improve our understanding of diabetes and its complications by understanding the role of environmental and genetic influences in diabetes and its associated complications.

YDX (Young Diabetes in Oxford) – Looking at the characteristics of people diagnosed with diabetes aged 45 years or younger.

HEAT (Helicobacter Eradication Aspirin Trial) – a study looking at whether treating a type of stomach infection called ‘Helicobacter’ in people who take aspirin might reduce their risk of developing stomach ulcers.

Clinical Practice Research Datalink

The practice is working with the Medicines & Healthcare products regulatory agency & National Institute for health research contributing anonymised data for the Clinical Practice Research datalink (CPRD).

CPRD data is used for approved medical and public health research including:

  • Investigating side effects of medicines
  • Investigating causes of disease and medical disorders and associated risk factors
  • Looking into the outcomes of treatments
  • Examining areas of unmet medical need
  • Identifying ways of improving screening or diagnosis
  • Evaluating which services or treatments work best

Find out more about CPRD.

RCGP Research and Surveillance centre

The practice is working with the RCGP research and surveillance centre contributing pseudonymised data for national research and surveillance. These data enable continuous monitoring of infections and diseases in the community and is used in ethically approved research.

Find out more about RCGP.

IQVIA Medical Research Extraction Scheme

The practice is working with the IQVIA Medical Research Extraction Scheme contributing pseudonymised data for medical and public health research. Please see the pdf link (9.83 MB) for more information.

  pdf Research Data Protection Privacy Notice (175 KB)